Although I am usually not inclined to posit speculations on why a particular drug does or doesn't do something, in this case I will. Im guessing that the higher doses of Anadrol cause enough appetite suppression (at least anecdotally) to make eating rather difficult. It can also increase insulin resistance and glucose intolerance (5). This has the effect of making macronutrient absorption more inefficient, and could also be a factor in reducing gains when the dosage goes over 100mgs/day. Unfortunately, Anadrol also has a reasonably profound effect on your body's natural hormonal system, on par with most other oral steroids , but not as bad as most injectables, and its certainly not as harsh on your lipid profile as many anabolics are
As for bodybuilders, Stanozolol has one interesting peculiarity demanded among them. It consists in the profound ability to lower sex hormone-binding globulin (SHBG) level resulting in efficiency growing of other steroids in stack with it. In particular, it raises the amount of biologically active free testosterone circulating in the blood. For this reason it is advisable always to use Stanozolol in stack with testosterone. Another one reason for this is as follows: Winstrol may be more prone than other anabolic steroids to increasing tendon brittleness. This happens due to Winstrol`s possibility to dry out the joint fluid, which can lead to joint pain and damages. Also both Stanozolol forms: tablets and injections have been noted to provoke adverse changes in cholesterol levels. Hence, monitoring of the lipid profile of the body (blood works) during cycle is advisable.