The actual cause of depression is not yet clear. However, doctors and scientists believe that it is a result of an imbalance in the chemicals signaling the brain. Studies are ongoing to identify the imbalance and the signaling chemicals. Various illnesses and some adverse life situations may spark depression. However, a majority of men with lower testosterone levels also exhibits depression signs. Most of them are obese or overweight. It points out the relation between depression and body fat. Average testosterone levels may reverse the situation for men.
A 2006 study determined that 1-testosterone has a high androgenic and anabolic potency even without being metabolized, so it can be characterized as a typical anabolic steroid. 1-Testosterone binds in a manner that is highly selective to the androgen receptor (AR) and has a high potency to stimulate AR-dependent transactivation . In vivo , an equimolar dose of 1-testosterone has the same potency to stimulate the growth of the prostate , the seminal vesicles and the androgen-sensitive levator ani muscle as the reference anabolic steroid testosterone propionate , but, unlike testosterone propionate, 1-testosterone also increases liver weight. 
Side effects of testosterone enanthate include symptoms of masculinization like acne , increased hair growth , voice changes , and increased sexual desire .  The drug is a synthetic androgen and anabolic steroid and hence is an agonist of the androgen receptor (AR), the biological target of androgens like testosterone and dihydrotestosterone (DHT).   It has strong androgenic effects and moderate anabolic effects, which make it useful for producing masculinization and suitable for androgen replacement therapy .  Testosterone enanthate is a testosterone ester and a long-lasting prodrug of testosterone in the body.    Because of this, it is considered to be a natural and bioidentical form of testosterone.