After the Kefauver Harris Amendment was passed in 1962, the . FDA began the DESI review process to ensure the safety and efficacy of drugs approved under the more lenient pre-1962 standards, including Dianabol.  In 1965, the FDA pressured CIBA to further document its legitimate medical uses, and re-approved the drug for treating post-menopausal osteoporosis and pituitary-deficient dwarfism .  After CIBA's patent exclusivity period lapsed, other manufacturers began to market generic metandienone in the .
In either case, both men and women, Anavar can be used for far longer than most oral anabolic steroids due to its low liver toxicity rating and further as it does not appear to taper off in benefit as fast as many other oral anabolic steroids. The majority of Anavar users will supplement for 6-8 weeks but longer durations of 12 weeks are not uncommon, especially during female contest preparation time. Keep in mind, the leaner you are the greater the results will be, meaning, they will be far more pronounced; for this reason most women will choose Anavar during the latter half of their diet to reap the greatest reward.