Clobetasol propionate usp 0.05

Clobetasol propionate comes as a foam, spray, cream, gel, ointment, or shampoo.  If applying a spray, gel, cream, or ointment to the skin, wash and dry the affected area and your hands before apply the medication. Cover the area with a thin layer of medication and rub it in gently. Allow the medication to dry before covering it with clothing. Do not wrap or bandage the area unless specified by your doctor. If using the clobetasol propionate shampoo to treat the scalp, part your hair to expose the affected area. Apply the shampoo to the affected area only on your dry scalp and massage it in gently. Let the shampoo sit for 15 minutes. Then add water, lather the shampoo in the area and rinse it out well. Because clobetasol propionate is a powerful corticosteroid, it should not be used for more than two weeks and should not be used on face, groin, or arm pit areas. Do not cover the affected area with makeup or cosmetics.

Therapeutic Category Allergic Disorders Analgesics & Antipyretic Anti-infectives Cardiovascular Central Nervous System Cough & Cold Eye Care Endocrine & Diabetes Gastrointestinal Hormones & Steroid Intravenous Fluids Muscloskeletal Oncology Other Products Respiratory Skin Care Vitamins & Minerals Supplement

The first isolation and structure identifications of prednisone and prednisolone were done in 1950 by Arthur Nobile . [29] [30] [31] The first commercially feasible synthesis of prednisone was carried out in 1955 in the laboratories of Schering Corporation, which later became Schering-Plough Corporation , by Arthur Nobile and coworkers. [32] They discovered that cortisone could be microbiologically oxidized to prednisone by the bacterium Corynebacterium simplex. The same process was used to prepare prednisolone from hydrocortisone . [33]

The following local adverse reactions are reported infrequently when topical corticosteroids are used as recommended. These reactions are listed in an approximately decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestations of Cushing syndrome, hyperglycemia, and glucosuria in some patients. In rare instances, treatment (or withdrawal of treatment) of psoriasis with corticosteroids is thought to have exacerbated the disease or provoked the pustular form of the disease, so careful patient supervision is recommended.

Clobetasol propionate usp 0.05

clobetasol propionate usp 0.05

The following local adverse reactions are reported infrequently when topical corticosteroids are used as recommended. These reactions are listed in an approximately decreasing order of occurrence: burning, itching, irritation, dryness, folliculitis, hypertrichosis, acneiform eruptions, hypopigmentation, perioral dermatitis, allergic contact dermatitis, maceration of the skin, secondary infection, skin atrophy, striae, and miliaria. Systemic absorption of topical corticosteroids has produced reversible HPA axis suppression, manifestations of Cushing syndrome, hyperglycemia, and glucosuria in some patients. In rare instances, treatment (or withdrawal of treatment) of psoriasis with corticosteroids is thought to have exacerbated the disease or provoked the pustular form of the disease, so careful patient supervision is recommended.

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